Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.71 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | BLM | P54132 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | SCN1A | P35498 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5051458 | 1.00 | ADRA2A (0.71) | ADRA2AADRA1ACYP2D6MEN1MAPK1 | |
| Hydrochloric Acid SCHEMBL9869689 | 0.98 | MEN1 (0.71) | ADRA2AADRA1ACYP2D6MEN1MAPK1 | |
| SCHEMBL18793769 | 0.85 | ACHE (0.54) | ADRA2AADRA1ACYP2D6MEN1MAPK1 | |
| SCHEMBL7786044 | 0.83 | CYP2D6 (0.50) | ADRA2AADRA1ACYP2D6MEN1MAPK1 | |
| SCHEMBL5051543 | 0.83 | CYP2D6 (0.50) | ADRA2AADRA1ACYP2D6MEN1MAPK1 | |
| Methoxamine SCHEMBL146222 | 0.83 | ADRA1A (1.00) | ADRA2AADRA1ACYP2D6MEN1MAPK1 | |
| Methoxamine SCHEMBL4258100 | 0.83 | ADRA1A (1.00) | ADRA2AADRA1ACYP2D6MEN1MAPK1 | |
| Methoxamine SCHEMBL4258097 | 0.83 | ADRA1A (1.00) | ADRA2AADRA1ACYP2D6MEN1MAPK1 | |
| Methoxamine SCHEMBL1043727 | 0.83 | ADRA1A (1.00) | ADRA2AADRA1ACYP2D6MEN1MAPK1 | |
| Methoxamine SCHEMBL7786034 | 0.83 | ADRA1A (1.00) | ADRA2AADRA1ACYP2D6MEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735142-B1 | Process for producing (R)-styrene oxides | SUMIKA FINE CHEMICALS CO LTD (JP) | 2001-10-24 | — | — | EP | disclosed |
| US-5717116-A | TREATING A MIXTURE OF PHENYLHALOGENOMETHYLCARBINOLS WITH A LIPASE IN THE PRESENCE OF A CARBOXYLATE FOLLOWED BY CYCLIZATION WITH A BASE | SUMIKA FINE CHEMICALS COMPANY, LIMITED (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0735142-A2 | Process for producing (R)-styrene oxides | SUMIKA FINE CHEMICAL COMPANY, LTD. (JP) | 1996-10-02 | — | — | EP | disclosed |