Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | GNRHR | P30968 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | ITK | Q08881 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8400685 | 0.83 | P2RX3 (0.34) | ACSS2KDM4EALDH1A1 | |
| SCHEMBL7792456 | 0.82 | BACE1 (0.39) | — | |
| SCHEMBL7792324 | 0.81 | ALDH1A1 (0.38) | ACSS2ALDH1A1GAA | |
| SCHEMBL7792081 | 0.79 | PTGDR2 (0.43) | KDM4EALDH1A1GAA | |
| SCHEMBL7792344 | 0.79 | PTGDR2 (0.43) | KDM4EALDH1A1GAA | |
| SCHEMBL7796343 | 0.79 | PTGDR2 (0.43) | KDM4EALDH1A1GAA | |
| SCHEMBL7792320 | 0.79 | L3MBTL1 (0.41) | ALDH1A1GAA | |
| SCHEMBL7792672 | 0.78 | KDM4E (0.32) | KDM4EALDH1A1GLAGAA | |
| SCHEMBL7796129 | 0.78 | CYP1A2 (0.43) | KDM4EALDH1A1GAA | |
| SCHEMBL7795876 | 0.78 | SMN1; SMN2 (0.38) | KDM4EALDH1A1GLAGAAGNRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0742210-B1 | 2-MERCAPTOBENZIMIDAZOLE DERIVATIVE AND ANTIHYPERLIPEMIC OR ANTIARTERIOSCLEROTIC AGENT CONTAINING THE SAME | FUJI PHOTO FILM CO LTD (JP) | 2001-11-21 | — | — | EP | disclosed |
| US-5962493-A | HYPOLIPEMIC AGENTS; ANTICHOLESTEROL AGENTS | FUJI PHOTO FILM CO., LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| EP-0742210-A1 | 2-MERCAPTOBENZIMIDAZOLE DERIVATIVE AND ANTIHYPERLIPEMIC OR ANTIARTERIOSCLEROTIC AGENT CONTAINING THE SAME | FUJI PHOTO FILM CO., LTD. (JP) | 1996-11-13 | — | — | EP | disclosed |