Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 4/20 | 0.52 |
| ▸ | HTR1A | P08908 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | DRD2 | P14416 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | HTR2B | P41595 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7793671 | 0.79 | ADRA1D (0.62) | HTR1AMAPTDRD2ADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL7029024 | 0.78 | ADRA1D (0.61) | HTR1AMAPTDRD2ADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL7029018 | 0.78 | ADRA1D (0.61) | HTR1AMAPTDRD2ADRA1DADRA1A | |
| SCHEMBL7796778 | 0.77 | HTR1A (0.53) | HTR7HTR1ALMNADRD2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7536565 | 0.76 | HTR1A (0.52) | HTR7HTR1ALMNADRD2SMN1; SMN2 | |
| SCHEMBL7536579 | 0.76 | HTR1A (0.56) | HTR7HTR1AMAPTDRD2KDM4E | |
| SCHEMBL7609804 | 0.75 | HTR1A (0.51) | HTR7HTR1ALMNAMAPTKDM4E | |
| SCHEMBL6070108 | 0.75 | DRD2 (0.51) | HTR1AMAPTDRD2KDM4ESMN1; SMN2 | |
| SCHEMBL6070259 | 0.75 | DRD2 (0.51) | HTR1AMAPTDRD2KDM4ESMN1; SMN2 | |
| SCHEMBL7542132 | 0.74 | DRD2 (0.62) | HTR7HTR1ALMNAMAPTDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1157017-A1 | N-SUBSTITUTED IMIDE DERIVATIVES WITH SEROTONERGIC ACTIVITY | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-11-28 | — | — | EP | disclosed |
| US-6306859-B1 | PIPERIDINE ALKYL IMIDES AS NEUROTRANSMITTERS | AMERICAN HOME PRODUCTS CORPORATION | 2001-10-23 | — | — | US | disclosed |
| WO-2000052002-A1 | N-SUBSTITUTED IMIDE DERIVATIVES WITH SEROTONERGIC ACTIVITY | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-09-08 | — | — | WO | disclosed |