Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.52 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.52 |
| ▸ | DRD4 | P21917 | 3/20 | 0.52 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HTR1B | P28222 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7536565 | 0.98 | HTR1A (0.52) | HTR1AMEN1KMT2AADRA1AADRA1D | |
| Hydrochloric Acid SCHEMBL7975411 | 0.95 | ADRA1D (0.49) | HTR1AMEN1KMT2AADRA1AADRA1D | |
| Hydrochloric Acid SCHEMBL7534854 | 0.81 | HTR1A (0.56) | HTR1AMEN1KMT2AADRA1AADRA1D | |
| SCHEMBL7786744 | 0.77 | HTR7 (0.52) | HTR1AMEN1KMT2AADRA1AADRA1D | |
| Fumaric Acid SCHEMBL7989873 | 0.75 | HTR1A (0.67) | HTR1AMEN1KMT2AADRA1AADRA1D | |
| SCHEMBL7758406 | 0.75 | HTR1A (0.59) | HTR1AMEN1KMT2AADRA1AADRA1D | |
| Hydrochloric Acid SCHEMBL7536688 | 0.72 | HTR1A (0.72) | HTR1AMEN1KMT2AADRA1AADRA1D | |
| SCHEMBL6933223 | 0.70 | HTR1A (0.75) | HTR1AMEN1KMT2AADRA1AADRA1D | |
| SCHEMBL6933222 | 0.70 | HTR1A (0.78) | HTR1AMEN1KMT2AADRA1AADRA1D | |
| SCHEMBL7698385 | 0.70 | HTR1A (0.59) | HTR1AMEN1KMT2AADRA1AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1157017-A1 | N-SUBSTITUTED IMIDE DERIVATIVES WITH SEROTONERGIC ACTIVITY | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-11-28 | — | — | EP | disclosed |
| WO-2000052002-A1 | N-SUBSTITUTED IMIDE DERIVATIVES WITH SEROTONERGIC ACTIVITY | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-09-08 | — | — | WO | disclosed |