Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 1/20 | 0.48 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25572016 | 0.84 | TGFBR1 (0.52) | STSTGFBR1GPR119KDM4EMAPT | |
| SCHEMBL17942453 | 0.83 | GPR119 (0.51) | TGFBR1GPR119KDM4EPKMMEN1 | |
| SCHEMBL22585197 | 0.81 | PTPN2 (0.47) | GPR119KDM4EMAPTTHRBPKM | |
| SCHEMBL4153384 | 0.79 | GPR119 (0.49) | STSTGFBR1GPR119TACR1 | |
| SCHEMBL7787125 | 0.78 | STS (0.58) | STSTGFBR1GPR119DPP4SCN9A | |
| SCHEMBL21722811 | 0.78 | STS (0.54) | STSTGFBR1GPR119KDM4EMAPT | |
| SCHEMBL4248138 | 0.77 | KDM4E (0.60) | STSTGFBR1GPR119KDM4EMAPT | |
| SCHEMBL3138097 | 0.76 | TGFBR1 (0.50) | STSTGFBR1GPR119KDM4EMAPT | |
| SCHEMBL5453826 | 0.75 | GPR119 (0.51) | GPR119KDM4EMAPTTHRBPKM | |
| SCHEMBL23329642 | 0.74 | ALDH1A1 (0.59) | STSTGFBR1GPR119KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100234603-A1 | Process for Making Substituted Aryl Sulfone Intermediates | LINGHU XIN | 2010-09-16 | — | — | US | disclosed |
| US-20100234604-A1 | Process for Making Substituted Aryl Sulfone Intermediates | LINGHU XIN | 2010-09-16 | — | — | US | disclosed |
| US-20100234604-A1 | Process for Making Substituted Aryl Sulfone Intermediates | LINGHU XIN | 2010-09-16 | — | — | US | disclosed |
| US-20100234603-A1 | Process for Making Substituted Aryl Sulfone Intermediates | LINGHU XIN | 2010-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234604-A1 | Process for Making Substituted Aryl Sulfone Intermediates | SULT1A1, SULT1E1, STS | STS 3/4885TGFBR1 4018/4885GPR119 4733/4885 |
| US-20100234603-A1 | Process for Making Substituted Aryl Sulfone Intermediates | SULT1A1, SULT1E1, STS | STS 3/4885TGFBR1 4018/4885GPR119 4733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.