Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PPIF | P30405 | 1/20 | 0.37 |
| ▸ | PPIA | P62937 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | STAT1 | P42224 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5860416 | 0.95 | RECQL (0.47) | ALDH1A1POLBKMT2AMEN1RAB9A | |
| SCHEMBL5860161 | 0.81 | POLB (0.49) | ALDH1A1POLBKMT2AMEN1RAB9A | |
| SCHEMBL7787285 | 0.73 | TRPM8 (0.45) | ALDH1A1POLBRAB9ANPC1L3MBTL1 | |
| SCHEMBL12045056 | 0.72 | KMT2A (0.45) | ALDH1A1POLBKMT2AMEN1RAB9A | |
| SCHEMBL7780059 | 0.71 | RAB9A (0.43) | ALDH1A1KMT2AMEN1RAB9ALMNA | |
| SCHEMBL2077718 | 0.71 | CYP2C19 (0.55) | ALDH1A1POLBKMT2AMEN1RAB9A | |
| SCHEMBL6489438 | 0.70 | POLB (0.51) | ALDH1A1POLBKMT2AMEN1RAB9A | |
| SCHEMBL3530965 | 0.69 | ALDH1A1 (0.51) | ALDH1A1POLBLMNAMAPTGAA | |
| SCHEMBL28359072 | 0.69 | ALDH1A1 (0.51) | ALDH1A1POLBLMNAMAPTGAA | |
| SCHEMBL5862734 | 0.69 | ALDH1A1 (0.46) | ALDH1A1POLBKMT2AMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140784-A2 | ION CHANNEL MODULATING AGENTS | NEUROSEARCH A/S (DK) | 2001-10-10 | — | — | EP | claimed |
| WO-2000037422-A2 | ION CHANNEL MODULATING AGENTS | NEUROSEARCH A/S (DK) | 2000-06-29 | — | — | WO | claimed |