Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5861519 | 0.94 | TRPM8 (0.47) | TRPM8KDM4EALDH1A1HIF1AMAPT | |
| SCHEMBL7780059 | 0.91 | RAB9A (0.43) | KDM4EALDH1A1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL5860443 | 0.85 | L3MBTL1 (0.41) | TRPM8KDM4EALDH1A1L3MBTL1NPC1 | |
| SCHEMBL5861527 | 0.84 | RAB9A (0.46) | TRPM8KDM4EALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL7780096 | 0.81 | ALDH1A1 (0.41) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5862688 | 0.81 | SMN1; SMN2 (0.53) | KDM4EALDH1A1MAPTHTTL3MBTL1 | |
| SCHEMBL5860161 | 0.80 | POLB (0.49) | ALDH1A1MAPTL3MBTL1NPC1RAB9A | |
| SCHEMBL5862800 | 0.80 | ATM (0.48) | KDM4EALDH1A1MAPTHTTL3MBTL1 | |
| SCHEMBL7788753 | 0.80 | ALDH1A1 (0.40) | KDM4EALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL5140898 | 0.77 | CYP1A2 (0.48) | TRPM8KDM4EALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140784-A2 | ION CHANNEL MODULATING AGENTS | NEUROSEARCH A/S (DK) | 2001-10-10 | — | — | EP | claimed |
| WO-2000037422-A2 | ION CHANNEL MODULATING AGENTS | NEUROSEARCH A/S (DK) | 2000-06-29 | — | — | WO | claimed |