Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5201914 | 0.91 | HTR1A (0.63) | HTR1A | |
| SCHEMBL5203900 | 0.91 | DRD2 (0.57) | HTR1ADRD2 | |
| SCHEMBL7787379 | 0.91 | DRD2 (0.57) | HTR1ADRD2 | |
| SCHEMBL7784884 | 0.91 | DRD2 (0.57) | HTR1ADRD2 | |
| SCHEMBL5203078 | 0.88 | KDM4E (0.56) | — | |
| SCHEMBL5201581 | 0.88 | HTR1A (0.63) | HTR1ADRD2 | |
| SCHEMBL7788871 | 0.88 | HTR1A (0.65) | HTR1ADRD2 | |
| SCHEMBL7784886 | 0.88 | HTR1A (0.55) | HTR1ADRD2 | |
| SCHEMBL7787373 | 0.88 | KDM4E (0.47) | HTR1ADRD2 | |
| SCHEMBL7788889 | 0.88 | HTR1A (0.57) | HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6251908-B1 | Piperazine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2001-06-26 | — | — | US | disclosed |