Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7780313 | 0.91 | TDP1 (0.41) | ALDH1A1LMNAGAAKMT2AMEN1 | |
| SCHEMBL7787600 | 0.91 | KMT2A (0.43) | ALDH1A1GAAKMT2AMEN1POLB | |
| SCHEMBL7780337 | 0.90 | ALDH1A1 (0.40) | ALDH1A1LMNAGAAKMT2AMEN1 | |
| SCHEMBL7785210 | 0.85 | SIGMAR1 (0.43) | ALDH1A1LMNAKMT2AMEN1POLB | |
| SCHEMBL7785298 | 0.82 | KMT2A (0.44) | ALDH1A1LMNAKMT2AMEN1POLB | |
| SCHEMBL7787602 | 0.82 | ALDH1A1 (0.44) | ALDH1A1LMNAGAAKMT2AMEN1 | |
| SCHEMBL7780560 | 0.81 | ALDH1A1 (0.44) | ALDH1A1LMNAGAAKMT2AMEN1 | |
| SCHEMBL7787655 | 0.81 | ALDH1A1 (0.44) | ALDH1A1LMNAGAAKMT2AMEN1 | |
| SCHEMBL7780429 | 0.81 | TDP1 (0.42) | ALDH1A1LMNAGAAKMT2AMEN1 | |
| SCHEMBL7789113 | 0.81 | KMT2A (0.44) | ALDH1A1GAAKMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |