Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7932216 | 0.96 | AKR1C3 (0.31) | AKR1C3 | |
| SCHEMBL7802511 | 0.95 | AKR1C3 (0.30) | AKR1C3 | |
| SCHEMBL7787200 | 0.89 | PTGS2 (0.31) | AKR1C3PTGS2 | |
| SCHEMBL7804341 | 0.87 | CA2 (0.37) | LMNAHTTSMN1; SMN2 | |
| SCHEMBL7794482 | 0.84 | CA2 (0.38) | AKR1C3LMNASMN1; SMN2 | |
| SCHEMBL7784784 | 0.83 | MT-CO2 (0.39) | AKR1C3LMNASMN1; SMN2 | |
| SCHEMBL7938680 | 0.83 | MT-CO2 (0.32) | — | |
| SCHEMBL7784776 | 0.82 | CA2 (0.43) | AKR1C3 | |
| SCHEMBL7800347 | 0.80 | MAPT (0.40) | AKR1C3PTGS2LMNASMN1; SMN2THRB | |
| SCHEMBL7784773 | 0.79 | MAPT (0.36) | AKR1C3PTGS2SMN1; SMN2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140067-A1 | ANTIVIRAL METHOD USING MEK INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000037141-A9 | COMBINATION CHEMOTHERAPY | WARNER LAMBERT CO (US) | 2000-12-07 | — | — | WO | disclosed |
| WO-2000040237-A1 | ANTIVIRAL METHOD USING MEK INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2000-07-13 | — | — | WO | disclosed |