Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.50 |
| ▸ | FABP2 | P12104 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29763737 | 1.00 | LMNA (0.50) | LMNAPTGS1MEN1KMT2AMAPT | |
| SCHEMBL13967517 | 0.89 | PTGS2 (0.46) | LMNAPTGS1MEN1KMT2AMAPT | |
| SCHEMBL10018702 | 0.86 | PTGS2 (0.48) | LMNAPTGS1MAPTPTGS2AKR1C3 | |
| SCHEMBL10091190 | 0.86 | MAPT (0.49) | LMNAPTGS1MEN1KMT2AMAPT | |
| SCHEMBL10091182 | 0.86 | MAPT (0.49) | LMNAPTGS1MEN1KMT2AMAPT | |
| SCHEMBL9228338 | 0.85 | GRM2 (0.42) | LMNAPTGS1MEN1KMT2AMAPT | |
| SCHEMBL10013948 | 0.84 | PTGS2 (0.47) | LMNAPTGS1MAPTPTGS2AKR1C3 | |
| SCHEMBL257801 | 0.83 | ACHE (0.50) | PTGS1MEN1KMT2APTGS2CYP2C9 | |
| SCHEMBL29893393 | 0.83 | HDAC7 (0.47) | LMNAPTGS1MEN1KMT2AMAPT | |
| SCHEMBL13220237 | 0.83 | HDAC7 (0.47) | LMNAPTGS1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1667958-A2 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | THE PROCTER & GAMBLE COMPANY (US) | 2006-06-14 | — | — | EP | claimed |
| WO-2005033063-A2 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | THE PROCTER & GAMBLE COMPANY (US) | 2005-04-14 | — | — | WO | claimed |
| US-20050075324-A1 | Melanin concentrating hormone antagonists | THE PROCTER & GAMBLE COMPANY (US) | 2005-04-07 | — | — | US | claimed |
| US-4422979-A | Fluoro-substituted biphenylyl compounds and processes | ETHYL CORPORATION (US) | 1983-12-27 | — | — | US | claimed |
| US-4371473-A | Preparation of 2-(2-fluoro-4-biphenylyl)propionic acid and corresponding nitride | ETHYL CORPORATION (US) | 1983-02-01 | — | — | US | claimed |
| US-4278516-A | Method for the preparation of 2-fluoro-4-monobromomethylbiphenyl | ETHYL CORPORATION (US) | 1981-07-14 | — | — | US | claimed |
| JP-57009757-A | — | — | None | — | — | JP | disclosed |
| JP-57045151-A | — | — | None | — | — | JP | disclosed |
| JP-55157530-A | — | — | None | — | — | JP | disclosed |
| JP-55157523-A | — | — | None | — | — | JP | disclosed |
| CN-115322070-A | Preparation method of p-alkyl phenyl o-fluorobenzene | 烟台盛华液晶材料有限公司 | 2022-11-11 | — | — | CN | disclosed |
| US-11387414-B2 | Spirobifluorene compounds for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2022-07-12 | — | — | US | disclosed |
| US-11236082-B2 | EZH2 inhibitors and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-02-01 | — | — | US | disclosed |
| US-4371473-A | Preparation of 2-(2-fluoro-4-biphenylyl)propionic acid and corresponding nitride | ETHYL CORPORATION (US) | 1983-02-01 | — | — | US | disclosed |
| JP-S5745151-A | ALPHA-SULFONYL 2-FLUORO-4-BIPHENYLYL PROPIONIC ACID DERIVATIVE | SAGAMI CHEM RES CENTER | 1982-03-13 | — | — | JP | disclosed |
| JP-S579757-A | ALPHA-SULFONYL 2-FLUORO-4-BIPHENYLYL ACETIC ACID DERIVATIVE | SAGAMI CHEM RES CENTER | 1982-01-19 | — | — | JP | disclosed |
| US-4278516-A | Method for the preparation of 2-fluoro-4-monobromomethylbiphenyl | ETHYL CORPORATION (US) | 1981-07-14 | — | — | US | disclosed |
| US-4278516-A | Method for the preparation of 2-fluoro-4-monobromomethylbiphenyl | ETHYL CORPORATION (US) | 1981-07-14 | — | — | US | disclosed |
| JP-S55157530-A | PREPARATION OF 3-FLUORO-4-PHENYLBENZALDEHYDE | SAGAMI CHEM RES CENTER | 1980-12-08 | — | — | JP | disclosed |
| JP-S55157523-A | HALOGENATED 3-FLUORO-4-PHENYLBENZAL | SAGAMI CHEM RES CENTER | 1980-12-08 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075324-A1 | Melanin concentrating hormone antagonists | MCHR1, MCHR2, MC1R | LMNA 4834/4885PTGS1 2265/4885MEN1 238/4885 |
| US-11387414-B2 | Spirobifluorene compounds for organic electroluminescent devices | PKD1, PIEZO1, AQP1 | LMNA 3591/4885PTGS1 1288/4885MEN1 500/4885 |
| US-11236082-B2 | EZH2 inhibitors and uses thereof | EZH2, EZH1, BMI1 | LMNA 2203/4885PTGS1 2734/4885MEN1 1860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.