Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP46A1 | Q9Y6A2 | 7/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.38 |
| ▸ | USP2 | O75604 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9240000 | 0.74 | LDHA (0.39) | ATMALDH1A1MAPK1LMNAMEN1 | |
| SCHEMBL1968241 | 0.74 | LDHA (0.44) | CYP46A1CYP1A2CYP3A4TSHRCLK4 | |
| SCHEMBL10782999 | 0.73 | ADORA2A (0.40) | TSHRATMALDH1A1USP2ADORA2A | |
| SCHEMBL18985923 | 0.73 | CYP1A2 (0.41) | CYP46A1NCOA1NCOA3CYP1A2CYP3A4 | |
| SCHEMBL7787933 | 0.73 | HCAR2 (0.35) | — | |
| SCHEMBL9651930 | 0.73 | HCAR2 (0.35) | — | |
| SCHEMBL5752103 | 0.72 | P2RX3 (0.35) | CYP1A2CYP3A4CYP2C19MEN1KMT2A | |
| SCHEMBL30315919 | 0.71 | BCAT2 (0.46) | CYP46A1CLK4ALDH1A1MEN1KMT2A | |
| SCHEMBL13531230 | 0.71 | MAPT (0.50) | CYP46A1NCOA1NCOA3TSHRATM | |
| SCHEMBL8577575 | 0.70 | ALDH1A1 (0.44) | CYP46A1ATMALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0332314-B1 | SOLVENT EXTRACTION PROCESS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-12-23 | — | — | EP | claimed |