Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7795271 | 0.80 | NPC1 (0.47) | TAS1R3TAS1R1TAS1R2HDAC6HDAC3 | |
| SCHEMBL7801296 | 0.76 | HDAC6 (0.41) | TAS1R3TAS1R1TAS1R2HDAC6HDAC3 | |
| SCHEMBL7797525 | 0.76 | NAMPT (0.50) | HDAC6HDAC3HDAC1HDAC2NAMPT | |
| SCHEMBL7796483 | 0.76 | HDAC6 (0.47) | HDAC6HDAC1MAPT | |
| SCHEMBL7796320 | 0.75 | NAMPT (0.42) | HDAC6HDAC3HDAC1HDAC2NAMPT | |
| SCHEMBL7796324 | 0.74 | HDAC6 (0.63) | HDAC6HDAC3HDAC1HDAC2NAMPT | |
| SCHEMBL7796321 | 0.74 | HDAC6 (0.50) | HDAC6HDAC3HDAC1HDAC2ALDH1A1 | |
| SCHEMBL7796971 | 0.74 | ALDH1A1 (0.43) | HDAC6HDAC3HDAC1HDAC2NAMPT | |
| SCHEMBL7795811 | 0.74 | POLB (0.40) | HDAC6HDAC1KDM4EMAPTALDH1A1 | |
| SCHEMBL7796728 | 0.73 | HDAC1 (0.53) | HDAC6HDAC3HDAC1HDAC2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010151317-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2010-12-29 | — | — | WO | disclosed |