Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | GPR142 | Q7Z601 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7795271 | 0.83 | NPC1 (0.47) | NAMPTSMN1; SMN2LMNAHDAC6HDAC3 | |
| SCHEMBL7790575 | 0.80 | ALDH1A1 (0.43) | NAMPTSMN1; SMN2ALDH1A1FAAHMAPK14 | |
| SCHEMBL7794883 | 0.79 | NAMPT (0.53) | NAMPT | |
| SCHEMBL7795270 | 0.76 | HPGD (0.43) | SMN1; SMN2ALDH1A1KMT2APTGER3NPC1 | |
| SCHEMBL7789524 | 0.75 | TAS1R3 (0.38) | NAMPTALDH1A1HDAC6HDAC3HDAC1 | |
| SCHEMBL7870443 | 0.72 | HDAC6 (0.52) | NAMPTSMN1; SMN2MAPK14HDAC6HDAC3 | |
| SCHEMBL7797525 | 0.70 | NAMPT (0.50) | NAMPTHDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL7795811 | 0.70 | POLB (0.40) | ALDH1A1MEN1KMT2ALMNAHDAC6 | |
| SCHEMBL7796483 | 0.70 | HDAC6 (0.47) | SMN1; SMN2LMNAHDAC6HDAC1 | |
| SCHEMBL7787409 | 0.68 | HDAC6 (0.47) | ALDH1A1CA1CA2HDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010151317-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2010-12-29 | — | — | WO | disclosed |