Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13880266 | 0.88 | DRD2 (0.46) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL7789933 | 0.83 | ALDH1A1 (0.46) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL13766161 | 0.80 | DRD2 (0.46) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL13880445 | 0.80 | DRD2 (0.43) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL7784188 | 0.78 | TRPM4 (0.44) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL21877452 | 0.75 | ALDH1A1 (0.46) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL29011630 | 0.73 | KDM4E (0.45) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL10049850 | 0.72 | MIF (0.39) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL10102360 | 0.71 | ALOX5 (0.44) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL21877223 | 0.71 | MAPT (0.46) | MEN1KMT2AKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042312-B1 | PHOTOCHROMIC INDENO-FUSED NAPHTHO[2,1-b]PYRANS | TRANSITIONS OPTICAL INC (US) | 2001-11-07 | — | — | EP | claimed |
| EP-1042312-B1 | PHOTOCHROMIC INDENO-FUSED NAPHTHO[2,1-b]PYRANS | TRANSITIONS OPTICAL INC (US) | 2001-11-07 | — | — | EP | disclosed |
| US-5869658-A | POLYMERIC ORGANIC HOST MATERIALS THAT CONTAIN OR THAT ARE COATED WITH THE NOVEL NAPHTHOPYRAN COMPOUNDS, LENSES | PPG INDUSTRIES, INC. (US) | 1999-02-09 | — | — | US | disclosed |