Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 6/20 | 0.40 |
| ▸ | CA2 | P00918 | 6/20 | 0.40 |
| ▸ | CA4 | P22748 | 6/20 | 0.40 |
| ▸ | CA6 | P23280 | 6/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | MAP3K9 | P80192 | 1/20 | 0.36 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11145048 | 0.88 | MAOA (0.44) | TRPM4ACHEBCHEKDM4EMEN1 | |
| SCHEMBL7742186 | 0.86 | MAOA (0.43) | TRPM4ACHEBCHEKDM4EMEN1 | |
| SCHEMBL10102234 | 0.85 | DRD2 (0.43) | TRPM4ALOX5NQO2ACHEBCHE | |
| SCHEMBL7789933 | 0.80 | ALDH1A1 (0.46) | ALOX5CA1CA2CA4CA6 | |
| SCHEMBL4714268 | 0.78 | SOS1 (0.49) | KDM4EMEN1KMT2ACYP2D6CYP2C9 | |
| SCHEMBL26634709 | 0.78 | MAP3K9 (0.39) | ALOX5CA1CA2CA4CA6 | |
| SCHEMBL31277199 | 0.78 | MAP3K9 (0.39) | ALOX5CA1CA2CA4CA6 | |
| SCHEMBL7789620 | 0.78 | MEN1 (0.45) | ALOX5CA1CA2CA4CA6 | |
| Fluorene SCHEMBL28192829 | 0.76 | TRPM4 (0.68) | TRPM4NQO2KDM4EMEN1MAPT | |
| SCHEMBL6209936 | 0.75 | ALOX5 (0.40) | ALOX5CA1CA2CA4CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042312-B1 | PHOTOCHROMIC INDENO-FUSED NAPHTHO[2,1-b]PYRANS | TRANSITIONS OPTICAL INC (US) | 2001-11-07 | — | — | EP | disclosed |