Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 6/20 | 0.46 |
| ▸ | DYRK2 | Q92630 | 6/20 | 0.46 |
| ▸ | DYRK1B | Q9Y463 | 6/20 | 0.46 |
| ▸ | DYRK3 | O43781 | 5/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7782141 | 0.88 | HPGDS (0.47) | DYRK1ADYRK1B | |
| SCHEMBL7789847 | 0.85 | PPARG (0.39) | PPARG | |
| SCHEMBL7782223 | 0.82 | MEN1 (0.47) | HPGDF3TAS1R3TAS1R1 | |
| SCHEMBL7782229 | 0.77 | CAPN1 (0.51) | — | |
| SCHEMBL7325294 | 0.76 | KMO (0.49) | HPGD | |
| SCHEMBL7787012 | 0.75 | ROCK2 (0.47) | DYRK1ADYRK1BF3 | |
| SCHEMBL7790079 | 0.74 | ROCK2 (0.43) | DYRK1ADYRK1B | |
| SCHEMBL722165 | 0.73 | BCAT2 (0.47) | HPGD | |
| SCHEMBL7314496 | 0.71 | PIN1 (0.48) | — | |
| SCHEMBL7787042 | 0.71 | DYRK1A (0.47) | DYRK1ADYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6251917-B1 | Benzamidoaldehydes and their use as cysteine protease inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 2001-06-26 | — | — | US | disclosed |