Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.53 |
| ▸ | CTSB | P07858 | 2/20 | 0.53 |
| ▸ | CTSS | P25774 | 2/20 | 0.53 |
| ▸ | CTSK | P43235 | 1/20 | 0.53 |
| ▸ | CHRNA1 | P02708 | 6/20 | 0.52 |
| ▸ | CHRNG | P07510 | 6/20 | 0.52 |
| ▸ | CHRNB1 | P11230 | 6/20 | 0.52 |
| ▸ | CHRND | Q07001 | 6/20 | 0.52 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.50 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGAV | P06756 | 1/20 | 0.50 |
| ▸ | TACR1 | P25103 | 2/20 | 0.48 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7798566 | 0.82 | SYK (0.55) | CTSLCTSBCTSSCTSKCAPN1 | |
| SCHEMBL9113871 | 0.81 | CTSL (0.73) | CTSLCTSBCTSSCTSKCAPN1 | |
| SCHEMBL17643540 | 0.78 | CTSL (0.76) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL22599593 | 0.77 | CTSL (0.70) | CTSLCTSBCTSSCTSKCAPN1 | |
| SCHEMBL3615384 | 0.76 | CTSL (0.65) | CTSLCTSBCTSSCTSKCAPN1 | |
| SCHEMBL3615382 | 0.76 | CTSL (0.65) | CTSLCTSBCTSSCTSKCAPN1 | |
| SCHEMBL14598315 | 0.76 | CTSS (0.64) | CTSLCTSBCTSSCTSK | |
| SCHEMBL7799692 | 0.75 | HTT (0.56) | CAPN1CAPN2 | |
| SCHEMBL7764124 | 0.75 | CTSL (0.71) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL8387597 | 0.75 | CTSL (0.71) | CTSLCTSBCTSSCTSKTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1159260-A1 | NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000055124-A2 | NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2000-09-21 | — | — | WO | disclosed |