Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 6/20 | 0.38 |
| ▸ | F11 | P03951 | 1/20 | 0.38 |
| ▸ | F2R | P25116 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7788171 | 0.99 | SMN1; SMN2 (0.43) | SMN1; SMN2ITGB3ITGA2BLMNAGAA | |
| SCHEMBL7788304 | 0.96 | ITGB3 (0.42) | SMN1; SMN2ITGB3ITGA2BF11F2R | |
| SCHEMBL7194899 | 0.84 | ITGB3 (0.44) | SMN1; SMN2ITGB3ITGA2BLMNAGAA | |
| SCHEMBL7781097 | 0.82 | KMT2A (0.46) | SMN1; SMN2ITGB3ITGA2BLMNAPOLB | |
| SCHEMBL7788768 | 0.81 | ATM (0.40) | SMN1; SMN2ITGB3ITGA2BLMNAGAA | |
| SCHEMBL7191718 | 0.81 | ALDH1A1 (0.36) | SMN1; SMN2ITGB3ITGA2BPOLB | |
| SCHEMBL7785595 | 0.81 | MMP12 (0.42) | SMN1; SMN2GAA | |
| SCHEMBL7781206 | 0.81 | ITGB3 (0.42) | ITGB3ITGA2B | |
| SCHEMBL7789969 | 0.80 | CYP26A1 (0.42) | SMN1; SMN2ITGB3ITGA2BLMNAGAA | |
| SCHEMBL7790178 | 0.80 | CTSA (0.41) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1147079-A2 | BETA-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS | Bayer Aktiengesellschaft (DE) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000041469-A2 | β-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-07-20 | — | — | WO | disclosed |