Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 6/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ITGAV | P06756 | 1/20 | 0.40 |
| ▸ | EEF2K | O00418 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7194899 | 0.94 | ITGB3 (0.44) | CTSAITGB3ITGA2BMAPTMAPK1 | |
| SCHEMBL7781206 | 0.92 | ITGB3 (0.42) | CTSAITGB3ITGA2BMAPTMAPK1 | |
| SCHEMBL7781180 | 0.91 | EEF2K (0.46) | CTSAITGB3ITGA2BEEF2KF10 | |
| SCHEMBL7789969 | 0.91 | CYP26A1 (0.42) | CTSAITGB3ITGA2BMAPTCYP26A1 | |
| SCHEMBL7785658 | 0.89 | LMNA (0.44) | CTSAITGB3ITGA2BMAPTMAPK1 | |
| SCHEMBL7788749 | 0.89 | ITGB3 (0.44) | CTSAITGB3ITGA2BMAPTMEN1 | |
| SCHEMBL7788355 | 0.88 | MMP12 (0.47) | ITGB3ITGA2BITGAVMMP12F10 | |
| SCHEMBL7786214 | 0.88 | S1PR3 (0.41) | CTSAITGB3ITGA2BMEN1KMT2A | |
| SCHEMBL7786241 | 0.87 | CTSA (0.46) | CTSAITGB3ITGA2BITGAVMEN1 | |
| SCHEMBL7790073 | 0.87 | CYP26A1 (0.46) | CTSAITGB3ITGA2BMAPTITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1147079-A2 | BETA-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS | Bayer Aktiengesellschaft (DE) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000041469-A2 | β-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-07-20 | — | — | WO | disclosed |