Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.41 |
| ▸ | MMP12 | P39900 | 2/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.39 |
| ▸ | AKT1 | P31749 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | NEK4 | P51957 | 2/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.39 |
| ▸ | PRKG2 | Q13237 | 2/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.39 |
| ▸ | PRKG1 | Q13976 | 2/20 | 0.39 |
| ▸ | PKN2 | Q16513 | 2/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7194899 | 0.94 | ITGB3 (0.44) | ITGB3ITGA2BF10MAPK1CTSA | |
| SCHEMBL7789969 | 0.92 | CYP26A1 (0.42) | ITGB3ITGA2BF10ROCK1UTS2R | |
| SCHEMBL7790178 | 0.92 | CTSA (0.41) | ITGB3ITGA2BF10MMP12MAPK1 | |
| SCHEMBL7781180 | 0.90 | EEF2K (0.46) | ITGB3ITGA2BF10CTSA | |
| SCHEMBL7785658 | 0.90 | LMNA (0.44) | ITGB3ITGA2BF10RPS6KA5AKT1 | |
| SCHEMBL7788749 | 0.89 | ITGB3 (0.44) | ITGB3ITGA2BUTS2RCTSAMEN1 | |
| SCHEMBL7786214 | 0.89 | S1PR3 (0.41) | ITGB3ITGA2BCTSACA1MEN1 | |
| SCHEMBL7786241 | 0.88 | CTSA (0.46) | ITGB3ITGA2BSUCNR1CTSAMEN1 | |
| SCHEMBL7790073 | 0.88 | CYP26A1 (0.46) | ITGB3ITGA2BF10ROCK1ROCK2 | |
| SCHEMBL7788355 | 0.87 | MMP12 (0.47) | ITGB3ITGA2BF10MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1147079-A2 | BETA-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS | Bayer Aktiengesellschaft (DE) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000041469-A2 | β-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-07-20 | — | — | WO | disclosed |