Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 6/20 | 0.55 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 2/20 | 0.46 |
| ▸ | MMP14 | P50281 | 2/20 | 0.46 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7794289 | 0.80 | SMN1; SMN2 (0.56) | CA1MMP2 | |
| SCHEMBL7784779 | 0.76 | CRHR1 (0.43) | CRHR1 | |
| SCHEMBL8007654 | 0.73 | CRHR1 (0.48) | CRHR1 | |
| SCHEMBL4255981 | 0.71 | FDPS (1.00) | FDPSFDFT1CA14CA1MMP8 | |
| SCHEMBL9034534 | 0.70 | GAA (0.46) | CRHR1 | |
| SCHEMBL9790803 | 0.68 | FDPS (0.66) | FDPSFDFT1CA14MMP8MMP14 | |
| SCHEMBL11446331 | 0.67 | PTK2 (0.51) | — | |
| SCHEMBL1198968 | 0.66 | HTT (0.46) | CRHR1 | |
| SCHEMBL31317020 | 0.66 | HTT (0.46) | CRHR1 | |
| SCHEMBL12909531 | 0.66 | KMT2A (0.50) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0762883-B1 | PYRIDYLBISPHOSPHONATES FOR USE AS A THERAPEUTICAL AGENT | LEIRAS OY (FI) | 2001-11-14 | — | — | EP | claimed |