Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28007758 | 0.80 | CES2 (0.46) | SRCCES2CES1ALDH1A1TSHR | |
| SCHEMBL819788 | 0.76 | SRC (0.54) | SRCCES2CES1ALDH1A1TDP1 | |
| SCHEMBL7616312 | 0.76 | CES2 (0.43) | SRCCES2CES1ALDH1A1TRPA1 | |
| SCHEMBL935224 | 0.76 | CES2 (0.43) | SRCCES2CES1ALDH1A1TDP1 | |
| SCHEMBL1412817 | 0.75 | ALDH1A1 (0.46) | SRCALDH1A1HSD17B10TDP1TSHR | |
| SCHEMBL5886893 | 0.75 | CYP2C19 (0.48) | SRCALDH1A1HSD17B10TDP1TSHR | |
| SCHEMBL9197961 | 0.74 | HTR6 (0.44) | SRCCES2CES1ALDH1A1HSD17B10 | |
| SCHEMBL9475159 | 0.74 | CES2 (0.41) | SRCCES2CES1ALDH1A1HSD17B10 | |
| SCHEMBL1095271 | 0.73 | TSHR (0.48) | SRCCES2CES1ALDH1A1HSD17B10 | |
| SCHEMBL5474109 | 0.73 | SRC (0.67) | SRCCES2CES1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3849664-A1 | PHENOXY-PYRIDYL-PYRIMIDINE COMPOUNDS AND METHODS OF USE | Genentech, Inc. (US) | 2021-07-21 | — | — | EP | disclosed |
| WO-2020056089-A1 | PHENOXY-PYRIDYL-PYRIMIDINE COMPOUNDS AND METHODS OF USE | GENENTECH, INC. (US) | 2020-03-19 | — | — | WO | disclosed |
| CN-103351315-A | General preparation method of sulfonyl chloride | UNIV BEIJING CHEMICAL | 2013-10-16 | — | — | CN | disclosed |
| CN-103193687-A | Method for preparing sulfonyl chloride in environment-friendly mode | UNIV BEIJING CHEMICAL | 2013-07-10 | — | — | CN | disclosed |
| CN-102040550-B | Inhibitors of cytosolic phospholipase A2 | WYETH CORP | 2012-10-03 | — | — | CN | disclosed |
| CN-102040550-A | Inhibitors of cytosolic phospholipase A2 | WYETH CORP | 2011-05-04 | — | — | CN | disclosed |
| CN-101184729-B | Cytosolic phospholipase A2Inhibitors | WYETH CORP | 2011-02-16 | — | — | CN | disclosed |
| CN-101184729-A | Cytosolic phospholipase A2Inhibitors | WYETH CORP (US) | 2008-05-21 | — | — | CN | disclosed |
| EP-0731388-B1 | An energy-sensitive resist material and a process for device fabrication using an energy-sensitive resist material | AT & T CORP (US) | 2001-11-14 | — | — | EP | disclosed |
| US-5656412-A | Energy-sensitive resist material and a process for device fabrication using an energy-sensitive resist material | LUCENT TECHNOLOGIES INC. (US) | 1997-08-12 | — | — | US | disclosed |
| EP-0731388-A2 | An energy-sensitive resist material and a process for device fabrication using an energy-sensitive resist material | AT&T Corp. (US) | 1996-09-11 | — | — | EP | disclosed |