Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 8/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | MMP14 | P50281 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7790467 | 0.76 | POLB (0.40) | NPC1RAB9AHTTSMN1; SMN2POLB | |
| SCHEMBL17187147 | 0.76 | CA12 (0.69) | FDPSCA14CA12CA2MMP2 | |
| SCHEMBL2037028 | 0.73 | POLB (0.47) | NPC1RAB9AHTTSMN1; SMN2POLB | |
| SCHEMBL7797073 | 0.72 | FDPS (0.61) | FDPSCA14CA12MMP8MMP14 | |
| SCHEMBL8415758 | 0.72 | POLB (0.48) | NPC1RAB9AHTTSMN1; SMN2POLB | |
| SCHEMBL7790447 | 0.71 | FDPS (0.69) | FDPSNPC1RAB9ACA12CA2 | |
| SCHEMBL5156538 | 0.70 | FDPS (1.00) | FDPSNPC1RAB9ACA12FDFT1 | |
| SCHEMBL8477791 | 0.70 | — | — | |
| SCHEMBL8167477 | 0.70 | FDPS (1.00) | FDPSNPC1RAB9ACA12MMP8 | |
| SCHEMBL15163986 | 0.70 | FDPS (0.67) | FDPSCA14CA12MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0762883-B1 | PYRIDYLBISPHOSPHONATES FOR USE AS A THERAPEUTICAL AGENT | LEIRAS OY (FI) | 2001-11-14 | — | — | EP | claimed |