Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7781999 | 0.84 | TSHR (0.44) | DHODHHPGDKDM4EALDH1A1NPSR1 | |
| SCHEMBL30128969 | 0.84 | DHODH (0.46) | DHODHHPGDKDM4EALDH1A1NPSR1 | |
| SCHEMBL1334120 | 0.84 | DHODH (0.46) | DHODHHPGDKDM4EALDH1A1NPSR1 | |
| SCHEMBL7786707 | 0.83 | LMNA (0.44) | DHODHHPGDKDM4EALDH1A1NPSR1 | |
| SCHEMBL6170807 | 0.81 | LMNA (0.50) | HPGDKDM4EALDH1A1NPSR1EGFR | |
| SCHEMBL9898507 | 0.79 | NR4A2 (0.50) | HPGDKDM4EALDH1A1NPSR1EGFR | |
| SCHEMBL1711290 | 0.74 | DHODH (0.56) | DHODHHPGDKDM4EALDH1A1NPSR1 | |
| SCHEMBL9015832 | 0.74 | PDE3B (0.49) | KDM4EHSD17B10 | |
| SCHEMBL2018471 | 0.73 | FABP3 (0.47) | DHODHHPGDKDM4EALDH1A1NPSR1 | |
| SCHEMBL9896760 | 0.72 | PLA2G2A (0.53) | DHODHHPGDKDM4EALDH1A1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801750-B1 | NOVEL SUBSTITUTED PHENANTHROPYRANS | PPG IND OHIO INC (US) | 2001-11-07 | — | — | EP | disclosed |
| EP-0801750-A4 | NOVEL SUBSTITUTED PHENANTHROPYRANS | PPG INDUSTRIES INC (US) | 1997-12-10 | — | — | EP | disclosed |
| EP-0801750-A1 | NOVEL SUBSTITUTED PHENANTHROPYRANS | PPG INDUSTRIES, INC. (US) | 1997-10-22 | — | — | EP | disclosed |
| US-5514817-A | PHOTOCHROMIC | PPG INDUSTRIES, INC. (US) | 1996-05-07 | — | — | US | disclosed |
| WO-1996004576-A1 | NOVEL SUBSTITUTED PHENANTHROPYRANS | PPG INDUSTRIES, INC. (US) | 1996-02-15 | — | — | WO | disclosed |