Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GNRHR | P30968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7795656 | 0.92 | NPC1 (0.42) | HSD17B10KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL7795876 | 0.87 | SMN1; SMN2 (0.38) | KDM4ESMN1; SMN2NPC1LMNAKMT2A | |
| SCHEMBL7796104 | 0.83 | HPGD (0.39) | HSD17B10KDM4ELMNAKMT2AMEN1 | |
| SCHEMBL8400685 | 0.83 | P2RX3 (0.34) | HSD17B10KDM4ERAB9AKMT2AMEN1 | |
| SCHEMBL7792456 | 0.82 | BACE1 (0.39) | KMT2A | |
| SCHEMBL7792324 | 0.80 | ALDH1A1 (0.38) | SMN1; SMN2LMNAALDH1A1GAAPOLB | |
| SCHEMBL7786096 | 0.79 | ACSS2 (0.35) | KDM4EALDH1A1GAAGNRHR | |
| SCHEMBL7792081 | 0.79 | PTGDR2 (0.43) | HSD17B10KDM4ESMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL7792344 | 0.79 | PTGDR2 (0.43) | HSD17B10KDM4ESMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL7796343 | 0.79 | PTGDR2 (0.43) | HSD17B10KDM4ESMN1; SMN2KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0742210-B1 | 2-MERCAPTOBENZIMIDAZOLE DERIVATIVE AND ANTIHYPERLIPEMIC OR ANTIARTERIOSCLEROTIC AGENT CONTAINING THE SAME | FUJI PHOTO FILM CO LTD (JP) | 2001-11-21 | — | — | EP | disclosed |
| US-5962493-A | HYPOLIPEMIC AGENTS; ANTICHOLESTEROL AGENTS | FUJI PHOTO FILM CO., LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| EP-0742210-A1 | 2-MERCAPTOBENZIMIDAZOLE DERIVATIVE AND ANTIHYPERLIPEMIC OR ANTIARTERIOSCLEROTIC AGENT CONTAINING THE SAME | FUJI PHOTO FILM CO., LTD. (JP) | 1996-11-13 | — | — | EP | disclosed |