Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7792820 | 0.74 | CES2 (0.34) | LMNACES2 | |
| SCHEMBL31545085 | 0.72 | LMNA (0.70) | LMNACES2MEN1CYP3A4ALOX15 | |
| SCHEMBL9706627 | 0.71 | LMNA (0.47) | LMNACES2MEN1CYP3A4ALOX15 | |
| SCHEMBL4402841 | 0.71 | LMNA (0.42) | LMNACES2MEN1CYP3A4ALOX15 | |
| SCHEMBL4440899 | 0.71 | LMNA (0.42) | LMNACES2MEN1CYP3A4ALOX15 | |
| SCHEMBL5698477 | 0.71 | LMNA (0.42) | LMNACES2MEN1CYP3A4ALOX15 | |
| SCHEMBL13726989 | 0.71 | LMNA (0.42) | LMNACES2MEN1CYP3A4ALOX15 | |
| SCHEMBL13782375 | 0.71 | LMNA (0.42) | LMNACES2MEN1CYP3A4ALOX15 | |
| SCHEMBL6435607 | 0.71 | LMNA (0.42) | LMNACES2MEN1CYP3A4ALOX15 | |
| SCHEMBL13985486 | 0.69 | LMNA (0.41) | LMNACES2MEN1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592677-B1 | Beta-LACTAM COMPOUND AND CEPHEM COMPOUND, AND PRODUCTION THEREOF | OTSUKA KAGAKU KK (JP) | 2001-11-07 | — | — | EP | disclosed |
| EP-0623622-B1 | PROCESS FOR PRODUCING CEPHEM COMPOUND | OTSUKA KAGAKU KK (JP) | 1999-10-06 | — | — | EP | disclosed |
| US-5693792-A | INTERMEDIATES FOR CEPHALOSPORIN ANTIBIOTICS | OTSUGA KAGAKU KABUSHIKI KAISHA (JP) | 1997-12-02 | — | — | US | disclosed |
| US-5656754-A | REACTING AN ALLENYL-B-LACTAM COMPOUND WITH AN ORGANOTIN COMPOUND | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-08-12 | — | — | US | disclosed |
| US-5470972-A | Process for preparing examethylenecephem compounds | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0623622-A1 | PROCESS FOR PRODUCING CEPHEM COMPOUND | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1994-11-09 | — | — | EP | disclosed |
| EP-0592677-A1 | Beta-LACTAM COMPOUND AND CEPHEM COMPOUND, AND PRODUCTION THEREOF | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1994-04-20 | — | — | EP | disclosed |