SCHEMBL7792233

SCHEMBL7792233

O=C(c1ccccc1)c1ccc(O)cc1S(=O)(=O)O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.62
MEN1 O00255 3/20 0.62
GAA P10253 2/20 0.62
USP2 O75604 1/20 0.62
KEAP1 Q14145 1/20 0.62
NFE2L2 Q16236 1/20 0.62
ALDH1A1 P00352 4/20 0.54
LMNA P02545 3/20 0.54
MAPT P10636 2/20 0.54
RAB9A P51151 2/20 0.47
NPC1 O15118 1/20 0.47
HPGD P15428 2/20 0.46
CYP1A2 P05177 1/20 0.46
PGR P06401 1/20 0.46
CYP2D6 P10635 1/20 0.46
SLC6A2 P23975 1/20 0.46
PDE4A P27815 1/20 0.46
MAPK1 P28482 1/20 0.46
CYP2C19 P33261 1/20 0.46
HRH1 P35367 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7787675 0.82 MAPT (0.51) KMT2AMEN1GAAUSP2KEAP1
SCHEMBL7788631 0.82 ALDH1A1 (0.49) KMT2AALDH1A1LMNAMAPTPGR
SCHEMBL300439 0.80 AKR1C3 (0.55) KMT2AGAAALDH1A1LMNAMAPT
SCHEMBL270224 0.80 ALDH1A1 (0.55) KMT2AMEN1GAAUSP2KEAP1
SCHEMBL8429016 0.80 ALDH1A1 (0.50) KMT2AMEN1GAAUSP2KEAP1
SCHEMBL30047153 0.79 ALDH1A1 (0.53) GAAALDH1A1LMNAHPGDCYP2D6
SCHEMBL2859237 0.79 ALDH1A1 (0.53) KMT2AMEN1GAAUSP2KEAP1
SCHEMBL29496654 0.79 AKR1C3 (0.53) KMT2AGAAALDH1A1LMNAMAPT
Water SCHEMBL27666388 0.79 AKR1C3 (0.53) KMT2AGAAALDH1A1LMNAMAPT
SCHEMBL28340031 0.79 AKR1C3 (0.53) KMT2AGAAALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023181691-A1 HAIR WASHING COMPOSITION 花王株式会社 2023-09-28 WO disclosed
US-20220226216-A1 HAIR TREATMENT METHOD KAO CORPORATION (JP) 2022-07-21 US disclosed
EP-3998060-A1 HAIR COSMETIC Kao Corporation (JP) 2022-05-18 EP disclosed
US-11234916-B2 Hair cosmetic KAO CORPORATION (JP) 2022-02-01 US disclosed
US-20210069081-A1 HAIR COSMETIC KAO CORPORATION (JP) 2021-03-11 US disclosed
EP-3741352-A1 HAIR COSMETIC COMPOSITION Kao Corporation (JP) 2020-11-25 EP disclosed
US-20190038532-A1 METHOD FOR TREATING HAIR KAO CORPORATION (JP) 2019-02-07 US disclosed
EP-0672405-B1 Hair treatment composition KAO CORP (JP) 2001-11-14 EP disclosed
EP-0743847-B1 HAIR COSMETIC COMPOSITION KAO CORP (JP) 2001-05-30 EP disclosed
US-6217855-B1 ELASTICITY KAO CORPORATION (JP) 2001-04-17 US disclosed
EP-0662314-B1 Method of hair treatment KAO CORP (JP) 1999-11-03 EP disclosed
US-5683685-A NAPHTHALENESULFONIC ACID AND/OR BENZOPHENONE SULFONIC ACID WITH ANIONIC AND/OR AMPHOTERIC SURFACTANT WITH OIL KAO CORPORATION (JP) 1997-11-04 US disclosed
EP-0743847-A1 HAIR COSMETIC COMPOSITION Kao Corporation (JP) 1996-11-27 EP disclosed
EP-0529437-B1 Hair treatment composition KAO CORP (JP) 1996-07-17 EP disclosed
EP-0672405-A1 Hair treatment composition KAO CORPORATION (JP) 1995-09-20 EP disclosed
WO-1995020375-A1 HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 1995-08-03 WO disclosed
EP-0662314-A1 Method of hair treatment Kao Corporation (JP) 1995-07-12 EP disclosed
EP-0529437-A1 Hair treatment composition Kao Corporation (JP) 1993-03-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210069081-A1 HAIR COSMETIC TYR, CUTA, H1-0 KMT2A 671/4885MEN1 266/4885GAA 1978/4885
US-20220226216-A1 HAIR TREATMENT METHOD POLR1C, ALDH7A1, CA7 KMT2A 2574/4885MEN1 1935/4885GAA 2027/4885
US-20190038532-A1 METHOD FOR TREATING HAIR TYR, POLR1C, CA7 KMT2A 1517/4885MEN1 4032/4885GAA 2602/4885
US-11234916-B2 Hair cosmetic TYR, CUTA, H1-0 KMT2A 671/4885MEN1 266/4885GAA 1978/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.