Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7792658 | 0.95 | FFAR1 (0.49) | FFAR1PPARAMAOBABCB1MTNR1A | |
| SCHEMBL8060522 | 0.95 | FFAR1 (0.49) | FFAR1PPARAMAOBABCB1MTNR1A | |
| SCHEMBL7796507 | 0.81 | NFKB1 (0.39) | FFAR1PTGER4PTGER3PTGER1PTGER2 | |
| SCHEMBL7910887 | 0.80 | FFAR1 (0.64) | FFAR1PTGER4PTGER3PTGER1PTGER2 | |
| SCHEMBL30066737 | 0.80 | RAB9A (0.61) | FFAR1PPARAMAOBABCB1MTNR1B | |
| SCHEMBL12542088 | 0.79 | FFAR1 (0.51) | FFAR1PPARAMAOBABCB1MTNR1A | |
| SCHEMBL7901019 | 0.78 | FFAR1 (0.51) | FFAR1PTGER4PTGER3PTGER1PTGER2 | |
| SCHEMBL7792549 | 0.77 | L3MBTL1 (0.43) | PPARAMAOBS1PR1S1PR5CASP3 | |
| SCHEMBL4953832 | 0.77 | FFAR1 (0.49) | FFAR1PTGER4PTGER3PTGER1PTGER2 | |
| SCHEMBL7786831 | 0.76 | S1PR1 (0.39) | FFAR1PPARAMAOBS1PR1S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0909267-B1 | NOVEL 1,3-DIPHENYLPROPANE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST TYROSINASE AND PROCESS FOR PREPARATION THEREOF | LG CHEMICAL LTD (KR) | 2001-11-21 | — | — | EP | disclosed |
| US-6093836-A | INHIBITORY ACTIVITY AGAINT MELANIN BIOSYNTHESIS; WHITENING SUBSTANCES FOR MEDICAMENTS, COSMETICS | LG CHEMICAL LTD. (KR) | 2000-07-25 | — | — | US | disclosed |