Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.49 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8060522 | 0.96 | FFAR1 (0.49) | FFAR1PPARAABCB1MTNR1AMTNR1B | |
| SCHEMBL7792552 | 0.95 | FFAR1 (0.47) | FFAR1PPARAABCB1MTNR1AMTNR1B | |
| SCHEMBL12542088 | 0.83 | FFAR1 (0.51) | FFAR1PPARAABCB1MTNR1AMTNR1B | |
| SCHEMBL30066737 | 0.82 | RAB9A (0.61) | FFAR1PPARAABCB1MTNR1BL3MBTL1 | |
| SCHEMBL12540543 | 0.80 | NPC1 (0.51) | FFAR1ABCB1MTNR1AMTNR1BL3MBTL1 | |
| SCHEMBL7796507 | 0.79 | NFKB1 (0.39) | FFAR1PPARAPPARGPPARDMAOB | |
| SCHEMBL7792657 | 0.78 | L3MBTL1 (0.46) | FFAR1PPARAMTNR1AMTNR1BL3MBTL1 | |
| SCHEMBL7795041 | 0.78 | ABCB1 (0.45) | FFAR1ABCB1MTNR1AMTNR1BHTR1A | |
| SCHEMBL7910887 | 0.77 | FFAR1 (0.64) | FFAR1 | |
| SCHEMBL7786615 | 0.77 | HDAC8 (0.59) | HDAC8TDP1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0909267-B1 | NOVEL 1,3-DIPHENYLPROPANE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST TYROSINASE AND PROCESS FOR PREPARATION THEREOF | LG CHEMICAL LTD (KR) | 2001-11-21 | — | — | EP | disclosed |
| US-6093836-A | INHIBITORY ACTIVITY AGAINT MELANIN BIOSYNTHESIS; WHITENING SUBSTANCES FOR MEDICAMENTS, COSMETICS | LG CHEMICAL LTD. (KR) | 2000-07-25 | — | — | US | disclosed |