Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 6/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8060518 | 0.83 | L3MBTL1 (0.46) | MAOBMTNR1AMTNR1BFFAR1PDCD1 | |
| SCHEMBL8060522 | 0.80 | FFAR1 (0.49) | ABCB1HTR1ADRD2MAOBMTNR1A | |
| SCHEMBL7792657 | 0.78 | L3MBTL1 (0.46) | MAOBMTNR1AMTNR1BFFAR1PDCD1 | |
| SCHEMBL7792658 | 0.78 | FFAR1 (0.49) | ABCB1HTR1ADRD2MAOBMTNR1A | |
| SCHEMBL7796609 | 0.77 | PTGER4 (0.41) | ABCB1MAOBPTGER4PTGER3PTGER2 | |
| SCHEMBL7796612 | 0.77 | PTGER4 (0.41) | ABCB1MAOBPTGER4PTGER3PTGER2 | |
| SCHEMBL7792549 | 0.76 | L3MBTL1 (0.43) | MAOBMTNR1AMTNR1BKDM4EALDH1A1 | |
| SCHEMBL7786831 | 0.76 | S1PR1 (0.39) | ABCB1HTR1ADRD2MAOBFFAR1 | |
| SCHEMBL7792552 | 0.76 | FFAR1 (0.47) | ABCB1MAOBMTNR1AMTNR1BFFAR1 | |
| SCHEMBL4953923 | 0.75 | LTA4H (0.63) | ABCB1HTR1ADRD2MAOBMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0909267-B1 | NOVEL 1,3-DIPHENYLPROPANE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST TYROSINASE AND PROCESS FOR PREPARATION THEREOF | LG CHEMICAL LTD (KR) | 2001-11-21 | — | — | EP | disclosed |