SCHEMBL7792920

SCHEMBL7792920

COc1c(C)cc(CC(=O)O)cc1C1CCCCC1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 4/20 0.49
THRA P10827 3/20 0.49
PTGDR2 Q9Y5Y4 9/20 0.47
PTGDR Q13258 4/20 0.40
PTGER2 P43116 1/20 0.40
S1PR1 P21453 1/20 0.40
S1PR5 Q9H228 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.39
CNR1 P21554 1/20 0.39
CNR2 P34972 1/20 0.39
CCNT1 O60563 1/20 0.38
CCNE1 P24864 1/20 0.38
CDK2 P24941 1/20 0.38
CDK9 P50750 1/20 0.38
CDK5 Q00535 1/20 0.38
CDK5R1 Q15078 1/20 0.38
ALDH1A1 P00352 1/20 0.38
GAA P10253 1/20 0.38
TSHR P16473 1/20 0.38
NFKB1 P19838 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7795938 0.87 THRA (0.51) THRBTHRAPTGDR2S1PR1S1PR5
SCHEMBL7796573 0.85 THRB (0.46) THRBTHRAPTGDR2PTGDRPTGER2
SCHEMBL7786559 0.84 THRB (0.46) THRBTHRAPTGDR2PTGDRPTGER2
SCHEMBL8430286 0.83 L3MBTL1 (0.45) PTGDR2PTGDRL3MBTL1CCNT1CCNE1
SCHEMBL7792886 0.82 THRB (0.47) THRBTHRAPTGDR2PTGDRPTGER2
SCHEMBL6568807 0.81 ALDH1A1 (0.38) PTGDR2CNR1CNR2ALDH1A1
SCHEMBL287411 0.81 THRB (0.49) THRBTHRAALDH1A1GAATSHR
SCHEMBL7796616 0.79 KMT2A (0.47) PTGDR2S1PR1CNR1CNR2ALDH1A1
SCHEMBL6567794 0.78 TNKS2 (0.42) PTGDR2ALDH1A1
SCHEMBL7933549 0.77 ALDH1A1 (0.47) THRBTHRAS1PR1L3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0823435-B1 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL CO (JP) 2001-11-21 EP disclosed
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5889095-A OXYGEN AND HEAT RESISTANCE SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1999-03-30 US disclosed
EP-0823435-A2 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-11 EP disclosed