Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 8/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8842878 | 0.84 | POLB (0.53) | ALDH1A1MAPTHPGDKMT2AKDM4E | |
| SCHEMBL7790430 | 0.84 | POLB (0.53) | ALDH1A1MAPTHPGDKMT2AKDM4E | |
| SCHEMBL7784713 | 0.80 | HDAC1 (0.48) | ALDH1A1HTTMAPTLMNAHPGD | |
| SCHEMBL7784715 | 0.80 | HDAC1 (0.48) | ALDH1A1HTTMAPTLMNAHPGD | |
| SCHEMBL7794807 | 0.80 | POLB (0.43) | ALDH1A1MAPTLMNAHPGDKMT2A | |
| SCHEMBL8842912 | 0.79 | SMPD1 (0.50) | KDM4E | |
| SCHEMBL8842915 | 0.79 | SMPD1 (0.50) | KDM4E | |
| SCHEMBL7793570 | 0.79 | MAPT (0.51) | ALDH1A1PKMHTTMAPTLMNA | |
| SCHEMBL8842889 | 0.79 | ALDH1A1 (0.47) | ALDH1A1MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7784722 | 0.79 | ALDH1A1 (0.47) | ALDH1A1MAPTKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0723969-B1 | Phosphonocarboxylic acid derivatives and their use in treating degenerative articular ailments | HOECHST AG (DE) | 2001-11-14 | — | — | EP | disclosed |
| EP-0723969-A1 | Phosphonocarboxylic acid derivatives and their use in treating degenerative articular ailments | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-07-31 | — | — | EP | disclosed |