Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | TUBB1 | Q9H4B7 | 10/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.44 |
| ▸ | TUBB | P07437 | 3/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.44 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.44 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.44 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.44 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.44 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.44 |
| ▸ | APP | P05067 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8842889 | 1.00 | ALDH1A1 (0.47) | ALDH1A1AOX1MAPTCYP1A2TUBB1 | |
| SCHEMBL7793570 | 0.90 | MAPT (0.51) | ALDH1A1MAPTCYP1A2APPMEN1 | |
| SCHEMBL7784710 | 0.85 | GAA (0.44) | ALDH1A1MAPTCYP1A2TUBB1TUBB4A | |
| SCHEMBL8842926 | 0.85 | GAA (0.44) | ALDH1A1MAPTCYP1A2TUBB1TUBB4A | |
| SCHEMBL8842877 | 0.84 | PTP4A3 (0.51) | ALDH1A1MAPTCYP1A2MEN1KMT2A | |
| SCHEMBL7794250 | 0.84 | PTP4A3 (0.51) | ALDH1A1MAPTCYP1A2MEN1KMT2A | |
| SCHEMBL7784713 | 0.82 | HDAC1 (0.48) | ALDH1A1MAPTTUBB1TUBB4ATUBB | |
| SCHEMBL7790430 | 0.82 | POLB (0.53) | ALDH1A1MAPTAPPMEN1KMT2A | |
| SCHEMBL8842878 | 0.82 | POLB (0.53) | ALDH1A1MAPTAPPMEN1KMT2A | |
| SCHEMBL7784715 | 0.82 | HDAC1 (0.48) | ALDH1A1MAPTTUBB1TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0723969-B1 | Phosphonocarboxylic acid derivatives and their use in treating degenerative articular ailments | HOECHST AG (DE) | 2001-11-14 | — | — | EP | disclosed |
| US-5627173-A | Phosphonoacetic acid derivatives and their use for treating degenerative joint disorders | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-06 | — | — | US | disclosed |
| EP-0723969-A1 | Phosphonocarboxylic acid derivatives and their use in treating degenerative articular ailments | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-07-31 | — | — | EP | disclosed |