Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7784253 | 0.86 | TSHR (0.39) | LMNAFOLH1ALDH1A1 | |
| SCHEMBL7790033 | 0.84 | FOLH1 (0.34) | FOLH1GAAEPHX2 | |
| SCHEMBL7790026 | 0.84 | CYP1A2 (0.38) | FOLH1ALDH1A1GAA | |
| SCHEMBL7784238 | 0.81 | FOLH1 (0.49) | FOLH1ALDH1A1 | |
| SCHEMBL7793672 | 0.81 | DGKA (0.42) | LMNAALDH1A1 | |
| SCHEMBL7793669 | 0.76 | FOLH1 (0.49) | LMNAFOLH1ALDH1A1 | |
| SCHEMBL7793684 | 0.74 | LMNA (0.51) | LMNAALDH1A1GAA | |
| SCHEMBL7793701 | 0.74 | LMNA (0.44) | LMNAALDH1A1GAAEPHX2 | |
| SCHEMBL23348428 | 0.74 | LMNA (0.57) | LMNAFOLH1ALDH1A1GAAEPHX2 | |
| SCHEMBL8104635 | 0.73 | LMNA (0.53) | LMNAALDH1A1GAAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0947503-B1 | 6,8-Dimethylmercaptooctanoic acid derivatives substituted on 6-S and/or 8-S by the 3-methylthiopropanoyl radical and pharmaceutical compositions for the treatment of cancerous tumours | GALDERMA RES & DEV (FR) | 2001-11-21 | — | — | EP | claimed |