Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7784253 | 0.86 | TSHR (0.39) | FOLH1 | |
| SCHEMBL7790026 | 0.84 | CYP1A2 (0.38) | FOLH1GAAKMT2A | |
| SCHEMBL7793680 | 0.84 | LMNA (0.43) | FOLH1EPHX2GAA | |
| SCHEMBL7784238 | 0.81 | FOLH1 (0.49) | FOLH1 | |
| SCHEMBL7793672 | 0.81 | DGKA (0.42) | MEN1KMT2A | |
| SCHEMBL7794209 | 0.76 | HDAC3 (0.33) | FOLH1HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL7793669 | 0.76 | FOLH1 (0.49) | FOLH1 | |
| SCHEMBL8104544 | 0.75 | EPHX2 (0.35) | FOLH1HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL7790037 | 0.74 | CTSK (0.32) | FOLH1HDAC1CTSKEPHX2HDAC4 | |
| SCHEMBL7324942 | 0.74 | HDAC8 (0.40) | FOLH1HDAC1HDAC3HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0947503-B1 | 6,8-Dimethylmercaptooctanoic acid derivatives substituted on 6-S and/or 8-S by the 3-methylthiopropanoyl radical and pharmaceutical compositions for the treatment of cancerous tumours | GALDERMA RES & DEV (FR) | 2001-11-21 | — | — | EP | claimed |