Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22193457 | 0.79 | TSHR (0.33) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL22193459 | 0.79 | TSHR (0.39) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7792822 | 0.79 | TSHR (0.45) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL2464293 | 0.76 | ALDH1A1 (0.40) | — | |
| SCHEMBL8654022 | 0.75 | TSHR (0.38) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL8666347 | 0.75 | TSHR (0.38) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7793715 | 0.74 | TSHR (0.40) | POLBNLRP3HDAC3HDAC4HDAC1 | |
| SCHEMBL22193460 | 0.74 | TSHR (0.31) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL649529 | 0.73 | TSHR (0.45) | — | |
| SCHEMBL6886176 | 0.73 | THRB (0.41) | POLBNLRP3HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710475-B1 | High refractive index and/or radio-opaque resins systems | ABONETICS LTD (GB) | 2001-11-21 | — | — | EP | disclosed |
| US-5679710-A | DENTAL COMPOSITES | LONDON HOSPITAL MEDICAL COLLEGE (GB) | 1997-10-21 | — | — | US | disclosed |
| EP-0710475-A1 | High refractive index and/or radio-opaque resins systems | THE LONDON HOSPITAL MEDICAL COLLEGE (GB) | 1996-05-08 | — | — | EP | disclosed |