Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7794741 | 0.89 | CHRM4 (0.42) | KMT2AKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL7797440 | 0.80 | HSP90AB1 (0.40) | KMT2AKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL7797896 | 0.80 | HSP90AB1 (0.51) | ALDH1A1CHRM4HSD17B10HSP90AB1LTB4R | |
| SCHEMBL8862704 | 0.76 | LTB4R (0.46) | ALDH1A1CHRM4HSD17B10HSP90AB1LTB4R | |
| SCHEMBL27379780 | 0.76 | SLC2A1 (0.47) | ALDH1A1HSD17B10HSP90AB1LTB4R | |
| SCHEMBL27355398 | 0.76 | ALDH1A1 (0.43) | KMT2AKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL9094776 | 0.75 | LTB4R (0.41) | ALDH1A1CHRM4HSD17B10HSP90AB1LTB4R | |
| SCHEMBL7497969 | 0.74 | PDE4A (0.56) | KMT2AMEN1ALDH1A1TRPV1POLB | |
| SCHEMBL27382274 | 0.73 | CHRM4 (0.39) | KMT2AKDM4EMEN1ALDH1A1GAA | |
| SCHEMBL27364630 | 0.72 | CHRM4 (0.38) | KMT2AKDM4EMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010031760-A1 | Method of treating a patient having precancerous lesions with quinazoline derivatives | PAMUKCU RIFAT (US) | 2001-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010031760-A1 | Method of treating a patient having precancerous lesions with quinazoline derivatives | MKI67, PCNA, NQO2 | KMT2A 1203/4885KDM4E 3242/4885MEN1 340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.