Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 2/20 | 0.38 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7797896 | 0.87 | HSP90AB1 (0.51) | HSP90AB1CHRM4LTB4RSLC2A1ALDH1A1 | |
| SCHEMBL7794741 | 0.85 | CHRM4 (0.42) | HSP90AB1CHRM4LTB4RLMNAIGFBP3 | |
| SCHEMBL9094776 | 0.84 | LTB4R (0.41) | HSP90AB1CHRM4LTB4RLMNAIGFBP3 | |
| SCHEMBL8862704 | 0.81 | LTB4R (0.46) | HSP90AB1CHRM4LTB4RIGFBP3SLC2A1 | |
| SCHEMBL27379780 | 0.81 | SLC2A1 (0.47) | HSP90AB1LTB4RSLC2A1ALDH1A1 | |
| SCHEMBL7794333 | 0.80 | KMT2A (0.45) | HSP90AB1CHRM4LTB4RMEN1KMT2A | |
| SCHEMBL27355398 | 0.77 | ALDH1A1 (0.43) | CHRM4LTB4RLMNAPDE5AMEN1 | |
| SCHEMBL7794732 | 0.77 | PDE4A (0.49) | HSP90AB1LTB4RLMNAPDE5AMEN1 | |
| SCHEMBL149749 | 0.75 | PDE4A (0.57) | HSP90AB1LTB4RLMNAIGFBP3PDE5A | |
| SCHEMBL8862871 | 0.75 | HSP90AB1 (0.40) | HSP90AB1CHRM4LTB4RIGFBP3SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010031760-A1 | Method of treating a patient having precancerous lesions with quinazoline derivatives | PAMUKCU RIFAT (US) | 2001-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010031760-A1 | Method of treating a patient having precancerous lesions with quinazoline derivatives | MKI67, PCNA, NQO2 | HSP90AB1 2725/4885CHRM4 3789/4885LTB4R 1536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.