Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7651931 | 0.66 | CHRNB2 (0.37) | CHRNB2CHRNA4 | |
| SCHEMBL8590825 | 0.59 | DYRK1A (0.43) | CHRNB2CHRNA4DYRK1AACHECA12 | |
| SCHEMBL31410678 | 0.58 | ANPEP (0.33) | DYRK1A | |
| SCHEMBL21959060 | 0.58 | MAOA (0.64) | ALDH1A1CA2CA9HSD17B10CA14 | |
| SCHEMBL31505403 | 0.58 | CHRNB2 (0.44) | CHRNB2CHRNA4ALDH1A1LMNACYP3A4 | |
| SCHEMBL8140136 | 0.58 | DRD2 (0.42) | CHRNB2CHRNA4 | |
| SCHEMBL8034552 | 0.58 | ESR1 (0.53) | LMNACYP3A4HSD17B10 | |
| SCHEMBL13049833 | 0.58 | ESR1 (0.53) | LMNACYP3A4HSD17B10 | |
| SCHEMBL13894961 | 0.58 | CHRNB2 (0.35) | CHRNB2CHRNA4DYRK1AACHECA12 | |
| SCHEMBL28910133 | 0.57 | CYP19A1 (0.48) | CHRNB2CHRNA4DYRK1ACA12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000044335-A2 | URIDYL PEPTIDE ANTIBIOTIC (UPA) DERIVATIVES, THEIR SYNTHESIS AND USE | MICROCIDE PHARMACEUTICALS, INC. (US) | 2000-08-03 | — | — | WO | claimed |
| WO-2000044335-A2 | URIDYL PEPTIDE ANTIBIOTIC (UPA) DERIVATIVES, THEIR SYNTHESIS AND USE | MICROCIDE PHARMACEUTICALS, INC. (US) | 2000-08-03 | — | — | WO | disclosed |