Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KHK | P50053 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.41 |
| ▸ | HTR3B | O95264 | 2/20 | 0.41 |
| ▸ | HTR3A | P46098 | 2/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6560382 | 0.84 | ALDH1A1 (0.50) | GAAKDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL7800857 | 0.79 | KMT2A (0.42) | GAANPSR1KDM4EALDH1A1KMT2A | |
| SCHEMBL3442752 | 0.77 | ALDH1A1 (0.53) | GAAKDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL7804710 | 0.76 | HTR1A (0.41) | HTR3A | |
| Piperazine SCHEMBL7803531 | 0.76 | ALDH1A1 (0.35) | GAAKDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL7804699 | 0.76 | MAPT (0.49) | GAAALDH1A1KMT2AMAPTFAAH | |
| SCHEMBL7795033 | 0.75 | MAPT (0.40) | GAAKDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL7800644 | 0.75 | RBP4 (0.46) | GAAKDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL7804720 | 0.74 | KMT2A (0.41) | GAANPSR1ALDH1A1KMT2AMAPT | |
| SCHEMBL7800642 | 0.74 | PDGFRB (0.39) | GAANPSR1ALDH1A1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1075469-A1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 2001-02-14 | — | — | EP | disclosed |
| WO-2000052001-A1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-09-08 | — | — | WO | disclosed |