Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.49 |
| ▸ | PGR | P06401 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | TNF | P01375 | 1/20 | 0.48 |
| ▸ | IL6 | P05231 | 1/20 | 0.48 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.48 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | GLUL | P15104 | 1/20 | 0.48 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.48 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6706306 | 0.88 | LMNA (0.58) | LMNAMAPTCYP19A1HIF1APGR | |
| SCHEMBL10957587 | 0.86 | LMNA (0.52) | LMNAMAPTCYP19A1HIF1APGR | |
| SCHEMBL10959603 | 0.85 | LMNA (0.55) | LMNAMAPTCYP19A1HIF1APGR | |
| SCHEMBL11325913 | 0.85 | LMNA (0.59) | LMNAMAPTCYP19A1HIF1APGR | |
| SCHEMBL10960995 | 0.84 | LMNA (0.50) | LMNAMAPTCYP19A1HIF1APGR | |
| Potassium Ion SCHEMBL10962185 | 0.84 | LMNA (0.56) | LMNAMAPTCYP19A1HIF1APGR | |
| SCHEMBL7793950 | 0.82 | SHBG (0.54) | LMNAMAPTHIF1APGRHSD17B10 | |
| SCHEMBL16564354 | 0.76 | PGR (0.51) | LMNAMAPTCYP19A1HIF1APGR | |
| SCHEMBL7793500 | 0.75 | SHBG (0.42) | LMNAMAPTCYP19A1HIF1APGR | |
| SCHEMBL10380227 | 0.73 | LMNA (0.74) | LMNAMAPTCYP19A1HIF1APGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863760-B1 | USE OF ANTIMINERALOCORTICOID COMPOUNDS AGAINST DRUG WITHDRAWAL SYNDROME | AVENTIS PHARMA SA (FR) | 2001-12-05 | — | — | EP | claimed |