Pyridine

Pyridine

SCHEMBL7795579

CCNc1ccccc1Cl.c1ccncc1

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ROCK2 O75116 2/20 0.43
GRK2 P25098 1/20 0.43
ADRA2C P18825 2/20 0.43
ADRA2B P18089 1/20 0.43
POLB P06746 1/20 0.41
SMN1; SMN2 Q16637 4/20 0.41
ALDH1A1 P00352 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
MAPT P10636 1/20 0.40
IDO1 P14902 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
LMNA P02545 1/20 0.39
HTT P42858 2/20 0.39
NPC1 O15118 1/20 0.39
PKM P14618 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1116563 0.87 IDO1 (0.48) ADRA2CADRA2BPOLBSMN1; SMN2ALDH1A1
Trimethylammonium SCHEMBL7802297 0.81 ALDH1A1 (0.45) ADRA2CADRA2BPOLBSMN1; SMN2ALDH1A1
SCHEMBL28887965 0.81 IDO1 (0.44) ADRA2CADRA2BPOLBSMN1; SMN2ALDH1A1
SCHEMBL7801503 0.76 KCNN4 (0.41) POLBSMN1; SMN2ALDH1A1MAPTIDO1
Pyridine SCHEMBL61964 0.75 LMNA (0.50) ROCK2GRK2ADRA2CADRA2BALDH1A1
SCHEMBL7801497 0.75 ALDH1A1 (0.55) SMN1; SMN2ALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL7795548 0.73 KDM4E (0.43) SMN1; SMN2ALDH1A1MEN1KMT2AKDM4E
1,2-Dichlorobenzene SCHEMBL1500545 0.73 TSHR (0.59) POLBSMN1; SMN2ALDH1A1CYP1A2CYP3A4
Pyridine SCHEMBL7017428 0.72 BACE1 (0.57) POLBALDH1A1MAPTIDO1HTT
SCHEMBL3908445 0.72 POLB (0.44) POLBSMN1; SMN2ALDH1A1CYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20010012899-A1 Oligomeric methine dyes CLARIANT FINANCE ( BVI) LIMITED 2001-08-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010012899-A1 Oligomeric methine dyes INMT, DDT, DDC ROCK2 4644/4885GRK2 2527/4885ADRA2C 1930/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.