Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | MLYCD | O95822 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11770803 | 0.87 | LMNA (0.46) | LMNAMAPTALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL10910683 | 0.84 | LMNA (0.47) | LMNAMAPTALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL10907926 | 0.84 | ALOX5 (0.46) | LMNAMAPTALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL2815024 | 0.83 | LMNA (0.42) | LMNAMAPTALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL5564538 | 0.83 | LMNA (0.50) | LMNAMAPTALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL14361963 | 0.82 | LMNA (0.46) | LMNAMAPTALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL4876557 | 0.79 | ALDH1A1 (0.61) | LMNAMAPTALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL11707329 | 0.79 | MAPT (0.36) | LMNAMAPTALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL11249889 | 0.76 | LMNA (0.49) | LMNAMAPTALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL10398307 | 0.76 | ALDH1A1 (0.49) | LMNAMAPTALDH1A1TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1099729-A2 | Mixtures of dispersive monoazo dyestuffs | DyStar Textilfarben GmbH & Co. Deutschland KG (DE) | 2001-05-16 | — | — | EP | disclosed |