Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 3/20 | 0.32 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.32 |
| ▸ | RHEB | Q15382 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7796348 | 0.85 | KDM4E (0.45) | AGTR1AGTR2MAPTKDM4ELMNA | |
| SCHEMBL7791855 | 0.82 | AGTR1 (0.35) | AGTR1AGTR2MAPTKDM4ELMNA | |
| SCHEMBL7786325 | 0.78 | HDAC6 (0.46) | PTGDR2MAPTHTTKDM4ELMNA | |
| SCHEMBL7796432 | 0.78 | HDAC6 (0.46) | PTGDR2MAPTHTTKDM4ELMNA | |
| SCHEMBL2857350 | 0.75 | DAPK3 (0.39) | AGTR1AGTR2PTGDR2MAPTALOX15 | |
| SCHEMBL7792482 | 0.72 | EPHX2 (0.32) | — | |
| SCHEMBL1260405 | 0.70 | PTPN1 (0.37) | PTGDR2MAPTALOX15HTTKDM4E | |
| SCHEMBL7792672 | 0.68 | KDM4E (0.32) | MAPTKDM4ELMNA | |
| SCHEMBL7792456 | 0.67 | BACE1 (0.39) | — | |
| SCHEMBL7786132 | 0.67 | EGLN1 (0.52) | HTTLMNARHEB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0742210-B1 | 2-MERCAPTOBENZIMIDAZOLE DERIVATIVE AND ANTIHYPERLIPEMIC OR ANTIARTERIOSCLEROTIC AGENT CONTAINING THE SAME | FUJI PHOTO FILM CO LTD (JP) | 2001-11-21 | — | — | EP | disclosed |
| US-5962493-A | HYPOLIPEMIC AGENTS; ANTICHOLESTEROL AGENTS | FUJI PHOTO FILM CO., LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| EP-0742210-A1 | 2-MERCAPTOBENZIMIDAZOLE DERIVATIVE AND ANTIHYPERLIPEMIC OR ANTIARTERIOSCLEROTIC AGENT CONTAINING THE SAME | FUJI PHOTO FILM CO., LTD. (JP) | 1996-11-13 | — | — | EP | disclosed |