SCHEMBL7792482

SCHEMBL7792482

CCC(=O)n1c(C(=O)SCCCCCSC(=O)c2nc3cc(Cl)c(C(F)(F)F)cc3n2C(=O)CC)nc2cc(C(F)(F)F)c(Cl)cc21

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.32
EGLN1 Q9GZT9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7791855 0.88 AGTR1 (0.35)
SCHEMBL7792672 0.78 KDM4E (0.32)
SCHEMBL7792456 0.76 BACE1 (0.39)
SCHEMBL8400685 0.73 P2RX3 (0.34)
SCHEMBL7792344 0.72 PTGDR2 (0.43)
SCHEMBL7796343 0.72 PTGDR2 (0.43)
SCHEMBL7792081 0.72 PTGDR2 (0.43)
SCHEMBL7795924 0.72 AGTR1 (0.35)
SCHEMBL7796129 0.71 CYP1A2 (0.43)
SCHEMBL7792324 0.71 ALDH1A1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0742210-B1 2-MERCAPTOBENZIMIDAZOLE DERIVATIVE AND ANTIHYPERLIPEMIC OR ANTIARTERIOSCLEROTIC AGENT CONTAINING THE SAME FUJI PHOTO FILM CO LTD (JP) 2001-11-21 EP disclosed
US-5962493-A HYPOLIPEMIC AGENTS; ANTICHOLESTEROL AGENTS FUJI PHOTO FILM CO., LTD. (JP) 1999-10-05 US disclosed
EP-0742210-A1 2-MERCAPTOBENZIMIDAZOLE DERIVATIVE AND ANTIHYPERLIPEMIC OR ANTIARTERIOSCLEROTIC AGENT CONTAINING THE SAME FUJI PHOTO FILM CO., LTD. (JP) 1996-11-13 EP disclosed