Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7795924 | 0.85 | AGTR1 (0.35) | KDM4ELMNAAGTR1AGTR2MAPT | |
| SCHEMBL7791855 | 0.81 | AGTR1 (0.35) | KDM4ELMNAAGTR1AGTR2SMN1; SMN2 | |
| SCHEMBL7786251 | 0.80 | ALDH1A1 (0.62) | KDM4ELMNAALDH1A1RECQLSMN1; SMN2 | |
| SCHEMBL7795665 | 0.73 | NPSR1 (0.56) | LMNAALDH1A1RECQLSMN1; SMN2MAPT | |
| SCHEMBL7792482 | 0.71 | EPHX2 (0.32) | — | |
| SCHEMBL7792672 | 0.67 | KDM4E (0.32) | KDM4ELMNAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7792456 | 0.66 | BACE1 (0.39) | KMT2A | |
| SCHEMBL7796432 | 0.66 | HDAC6 (0.46) | KDM4ELMNAALDH1A1RECQLSMN1; SMN2 | |
| SCHEMBL7786325 | 0.66 | HDAC6 (0.46) | KDM4ELMNAALDH1A1RECQLSMN1; SMN2 | |
| SCHEMBL24549187 | 0.66 | KDM4E (0.49) | KDM4ELMNAAGTR1AGTR2RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0742210-B1 | 2-MERCAPTOBENZIMIDAZOLE DERIVATIVE AND ANTIHYPERLIPEMIC OR ANTIARTERIOSCLEROTIC AGENT CONTAINING THE SAME | FUJI PHOTO FILM CO LTD (JP) | 2001-11-21 | — | — | EP | disclosed |
| US-5962493-A | HYPOLIPEMIC AGENTS; ANTICHOLESTEROL AGENTS | FUJI PHOTO FILM CO., LTD. (JP) | 1999-10-05 | — | — | US | disclosed |