Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 8/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.67 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.67 |
| ▸ | GLA | P06280 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | CASP1 | P29466 | 2/20 | 0.67 |
| ▸ | CASP7 | P55210 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | MAOA | P21397 | 2/20 | 0.67 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.67 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.67 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.67 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.67 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.67 |
| ▸ | NQO2 | P16083 | 1/20 | 0.67 |
| ▸ | DRD1 | P21728 | 1/20 | 0.67 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11057550 | 0.89 | ACHE (0.67) | ACHEKDM4EALDH1A1HSD17B10CHRM1 | |
| SCHEMBL9709249 | 0.85 | MAOA (0.72) | ACHEKDM4EALDH1A1HSD17B10CHRM1 | |
| Aminacrine SCHEMBL14999 | 0.82 | HSD17B10 (1.00) | ACHEKDM4EALDH1A1HSD17B10CHRM1 | |
| Aminacrine SCHEMBL29354393 | 0.82 | HSD17B10 (1.00) | ACHEKDM4EALDH1A1HSD17B10CHRM1 | |
| SCHEMBL4163642 | 0.81 | KDM4E (0.72) | ACHEKDM4EALDH1A1HSD17B10CHRM1 | |
| SCHEMBL20008613 | 0.80 | NR4A2 (0.53) | ACHECHRM1KMT2APOLBLMNA | |
| Aminacrine SCHEMBL4907467 | 0.80 | HSD17B10 (0.95) | ACHEKDM4EALDH1A1HSD17B10CHRM1 | |
| Aminacrine SCHEMBL14482032 | 0.80 | HSD17B10 (0.95) | ACHEKDM4EALDH1A1HSD17B10CHRM1 | |
| Aminacrine SCHEMBL18989123 | 0.80 | HSD17B10 (0.95) | ACHEKDM4EALDH1A1HSD17B10CHRM1 | |
| Aminacrine SCHEMBL635597 | 0.80 | RAB9A (1.00) | ACHEKDM4EALDH1A1HSD17B10CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303385-B2 | TRANSPARENT SUPPORT MATERIAL, LAYER OF WATER-INSOLUBLE COPOLYMERS THAT ARE COMPOSED OF N,N-DIMETHYLACRYLAMIDE OR N,N-DIMETHYLMETHACRYLAMIDE, FLUOROPHORE WHICH IS COVALENTLY BONDED TO THE POLYMER | NOVARTIS AG (CH) | 2001-10-16 | — | — | US | disclosed |
| US-20010018217-A1 | Acrylic amide copolymer crosslinked with diolefins; covalently bonded to pH sensitive fluorescent dyes; physiological solution, i.e. blood; ionic strength-independent | BARNARD STEVEN MARK (US) | 2001-08-30 | — | — | US | disclosed |
| US-6252024-B1 | WATER INSOLUBLE COPOLYMER | NOVARTIS AG (CH) | 2001-06-26 | — | — | US | disclosed |
| EP-0862741-B1 | OPTICAL SENSOR SYSTEM FOR THE DETERMINATION OF PH VALUES INDEPENDENTLY OF IONIC STRENGTH | NOVARTIS AG (CH) | 2001-04-25 | — | — | EP | disclosed |
| EP-0758361-B1 | POLYMERISABLE COMPOSITION AND THE USE THEREOF | NOVARTIS AG (CH) | 2000-11-15 | — | — | EP | disclosed |
| US-5922612-A | INDEPENDENT, REVERSIBLE FLUORESCENCE SPECTROMETRY OF SAMPLE USING TWO OPTICAL SENSORS COMPOSED OF A CARRIER EACH COATED WITH DIFFERENT WATER INSOLUBLE BUT HYDROPHILIC ADDITION POLYMER LOADED WITH THE SAME FLUORESCENT DYE | NOVARTIS CORPORATION (US) | 1999-07-13 | — | — | US | disclosed |
| EP-0758451-B1 | OPTICAL SENSOR SYSTEM FOR DETERMINING pH VALUES AND IONIC STRENGTHS | NOVARTIS AG (CH) | 1999-01-20 | — | — | EP | disclosed |
| US-5852126-A | Polymerisable composition and the use thereof | NOVARTIS AG (CH) | 1998-12-22 | — | — | US | disclosed |
| EP-0862741-A1 | OPTICAL SENSOR SYSTEM FOR THE DETERMINATION OF PH VALUES INDEPENDENTLY OF IONIC STRENGTH | Novartis AG (CH) | 1998-09-09 | — | — | EP | disclosed |
| WO-1997015832-A1 | OPTICAL SENSOR SYSTEM FOR THE DETERMINATION OF PH VALUES INDEPENDENTLY OF IONIC STRENGTH | NOVARTIS AG (CH) | 1997-05-01 | — | — | WO | disclosed |
| CN-1147301-A | Optical sensor system for determining pH values and ionic strength | CIBA GEIGY AG (CH) | 1997-04-09 | — | — | CN | disclosed |
| CN-1147267-A | Polymerizable composition and application thereof | CIBA GEIGY AG (CH) | 1997-04-09 | — | — | CN | disclosed |
| EP-0758361-A1 | POLYMERISABLE COMPOSITON AND THE USE THEREOF | Novartis AG (CH) | 1997-02-19 | — | — | EP | disclosed |
| EP-0758451-A1 | OPTICAL SENSOR SYSTEM FOR DETERMINING pH VALUES AND IONIC STRENGTHS | Novartis AG (CH) | 1997-02-19 | — | — | EP | disclosed |
| WO-1995030148-A1 | OPTICAL SENSOR SYSTEM FOR DETERMINING pH VALUES AND IONIC STRENGTHS | CIBA-GEIGY AG (CH) | 1995-11-09 | — | — | WO | disclosed |
| WO-1995029959-A1 | POLYMERISABLE COMPOSITON AND THE USE THEREOF | CIBA-GEIGY AG (CH) | 1995-11-09 | — | — | WO | disclosed |
| EP-0469042-A4 | NOVEL OLIGODEOXYNUCLEOTIDES WITH 5'-LINKED CHEMICAL GROUPS, METHOD OF PRODUCTION THEREOF AND USE THEREOF | US HEALTH (US) | 1992-07-01 | — | — | EP | disclosed |
| EP-0469042-A1 | NOVEL OLIGODEOXYNUCLEOTIDES WITH 5'-LINKED CHEMICAL GROUPS, METHOD OF PRODUCTION THEREOF AND USE THEREOF | THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce (US) | 1992-02-05 | — | — | EP | disclosed |
| WO-1990012802-A1 | NOVEL OLIGODEOXYNUCLEOTIDES WITH 5'-LINKED CHEMICAL GROUPS, METHOD OF PRODUCTION THEREOF AND USE THEREOF | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, U.S. DEPARTMENT OF COMMERCE (US) | 1990-11-01 | — | — | WO | disclosed |
| US-4462993-A | REACTION WITH A SUGAR IN PRESENCE OF ACID CATALYST | BIOGAL GYOGYSZERGYAR (HU) | 1984-07-31 | — | — | US | disclosed |