Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.37 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7795627 | 0.87 | SMN1; SMN2 (0.39) | RAB9ANPC1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL7796051 | 0.81 | MAPK1 (0.43) | MAPK1RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL8329698 | 0.79 | ALDH1A1 (0.48) | RAB9ANPC1SMN1; SMN2MAPTTP53 | |
| SCHEMBL7334309 | 0.75 | NPC1 (0.49) | MAPK1RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL8009012 | 0.75 | RAB9A (0.56) | MAPK1RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL7795117 | 0.74 | ITGB3 (0.44) | SMN1; SMN2KDM4EPOLBALDH1A1 | |
| Hydrochloric Acid SCHEMBL7330565 | 0.74 | RAB9A (0.55) | MAPK1RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL7796055 | 0.73 | ITGB1 (0.41) | RAB9ANPC1SMN1; SMN2MAPTLMNA | |
| SCHEMBL2008979 | 0.73 | MAPK1 (0.56) | MAPK1RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL7796035 | 0.73 | MAPT (0.40) | RAB9ANPC1SMN1; SMN2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010034445-A1 | Vitronectin receptor antagonists | SMITHKLINE BEECHAM CORPORATION | 2001-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010034445-A1 | Vitronectin receptor antagonists | ADGRF1, GPR174, CALCRL | MAPK1 665/4885RAB9A 2305/4885NPC1 792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.