SCHEMBL7796424

SCHEMBL7796424

CCCCCC(C)(C)c1cc(C(=O)O)cc(CC)c1OC

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 1/20 0.40
CNR2 P34972 4/20 0.37
CNR1 P21554 3/20 0.37
PLA2G2D Q9UNK4 1/20 0.37
TPMT P51580 4/20 0.36
TP53 P04637 2/20 0.36
TSHR P16473 2/20 0.36
KDM4E B2RXH2 1/20 0.36
CYP3A4 P08684 1/20 0.36
MAPT P10636 1/20 0.36
ALOX15 P16050 1/20 0.36
ACAT1 P24752 1/20 0.36
SOAT1 P35610 1/20 0.36
TNFRSF1A P19438 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7786612 0.88 TNFRSF1A (0.46) PLA2G2ACNR2CNR1TPMTTP53
SCHEMBL7792421 0.87 PLA2G2A (0.40) PLA2G2ACNR2CNR1TPMTTP53
SCHEMBL7796420 0.85 TPMT (0.39) PLA2G2ATPMTTSHRTNFRSF1A
SCHEMBL7792498 0.85 TPMT (0.43) TPMTTSHRKDM4ETNFRSF1A
SCHEMBL7944998 0.83 ESR1 (0.40) CNR2CNR1
SCHEMBL3809058 0.82 PLA2G2A (0.40) PLA2G2ACNR2CNR1PLA2G2DTP53
SCHEMBL7795937 0.82 THRB (0.44) CNR2CNR1TP53TSHRKDM4E
SCHEMBL7792476 0.82 TNFRSF1A (0.46) TPMTTSHRTNFRSF1A
SCHEMBL8401557 0.81 ALOX5 (0.51) CNR2CNR1TP53TSHRKDM4E
SCHEMBL7794855 0.80 THRA (0.45) CNR2CNR1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0823435-B1 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL CO (JP) 2001-11-21 EP disclosed
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5889095-A OXYGEN AND HEAT RESISTANCE SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1999-03-30 US disclosed
EP-0823435-A2 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-11 EP disclosed